
Hello, I am Dr. Seojin Jae, Chief Dermatologist at Karin Clinic.
When meeting patients in my clinic, I very frequently hear the same concern: "Doctor, I feel like my facial contour is collapsing, and at the same time, my skin feels dull and dry. What should I do?" This happens because aging never shows up in just one form. The sagging of skin caused by gravity and the thinning of skin accompanied by fine lines due to the loss of moisture and collagen usually progress simultaneously.
In these cases, the combination I recommend most confidently and frequently is the synergistic pairing of 'Ultherapy' and 'Rejuran.' Today, I will explain in detail why the effects are maximized when these two titans of anti-aging treatments come together.

1. Ultherapy: Lifting That Rebuilds the Pillars Deep Within the Skin
Ultherapy is a lifting device that utilizes High-Intensity Focused Ultrasound (HIFU) energy. Much like focusing sunlight through a magnifying glass to burn a spot on a piece of paper, it concentrates ultrasound energy onto deep target layers within the skin to create thermal coagulation points. The greatest feature of Ultherapy is that it delivers energy all the way down to the SMAS (Superficial Muscular Aponeurotic System) layerโthe exact deep layer pulled during a surgical faceliftโwithout causing any damage to the skin surface.
As the heated tissue contracts, it creates an immediate tightening effect. Over the following months, as new collagen and elastin regenerate, sagging eyes, eyelids, cheeks, double chins, and jawlines become smoothly lifted.
Simply put, Ultherapy plays the role of firmly rebuilding the collapsed "pillars" and structural framework inside skin that has succumbed to aging.

2. Rejuran: A Skin Booster That Fundamentally Improves the Dermal Environment
Rejuran is a treatment that directly injects PN (Polynucleotide), a biocompatible substance extracted from salmon DNA, into the dermal layer. While Ultherapy targets the deep muscular framework, Rejuran directly targets the dermisโthe layer we commonly refer to as the actual "skin texture."
By inducing regeneration in a damaged and thinned dermal layer, it increases skin thickness, balances oil and moisture levels, and strengthens the skin barrier. It restores the overall skin "texture" and "glow" by improving fine lines, minimizing pores, and clarifying the complexion.
Rejuran plays the role of adding premium fertilizer to a dry, barren "soil," transforming it into healthy, deeply hydrated skin.
3. Rebuilding the Framework and Completing the Interior: The Ultherapy + Rejuran Synergy
So, why is it so beneficial to receive these two treatments together? To jump straight to the conclusion: it is because they target completely different skin layers and their complementary roles match perfectly. I often compare this combination to "remodeling a house."
๐ Synergy Point 1: Three-Dimensional (3D) Anti-Aging (The Difference in Depth)
When a house is old and deteriorating, simply replacing the wallpaper (the surface) won't make the structure sturdy, and rebuilding just the pillars (the framework) won't make the interior beautiful. While Ultherapy pulls up sagging tissue from the deepest layer (SMAS) to define the facial "contour," Rejuran densely fills the middle layer (dermis) to smooth out the skin's "texture." By tackling both the deep and shallow layers at once, a flawless anti-aging transformation is achieved.
๐ Synergy Point 2: Maximizing Collagen Production
Ultherapy triggers natural collagen production through thermal stimulation. For skin cells to actively produce collagen during this process, premium "materials" and a healthy "environment" are absolutely essential. Rejuran (the PN component) provides precisely those excellent raw materials and the ideal regenerative environment. If Ultherapy flips the switch to start up the factory, Rejuran pours in the high-grade raw materials. Consequently, you can expect a much faster and more powerful skin regeneration and elasticity boost compared to receiving either treatment alone.
๐ Synergy Point 3: Compensating for Post-Treatment Dryness
After receiving energy-based laser or ultrasound treatments like Ultherapy, some patients temporarily experience dryness because the moisture inside the skin evaporates. Combining this with Rejuranโwhich possesses outstanding moisture-retention and regenerative capabilitiesโperfectly guards against post-laser dryness, while accelerating skin soothing and recovery.
4. Ideal Candidates for the Ultherapy + Rejuran Combination
This perfect synergistic combination is highly recommended for those who:
Are concerned about a collapsing facial line and a dulled, sagging jawline.
Have thin, dry skin that feels like it is losing its elasticity and sagging helplessly.
Notice a prominent increase in shallow fine lines all over the face, especially around the eyes and mouth.
Want their peak skin condition and crisp facial contours ahead of a wedding or a major event.
Lack the time to undergo multiple separate treatments and want definitive, comprehensive results all at once.
When it comes to anti-aging, a simple, one-dimensional approachโlike erasing a single wrinkle or just pulling the skin tightโcannot bring out natural beauty. You must simultaneously improve the structural issues deep within the skin along with the visible quality of the skin surface to truly restore your natural, youthful, and effortless beauty.
Of course, no matter how excellent a treatment combination is, the procedure design, energy distribution, and injection volume must be delicately tailored to each individual's skin thickness, degree of sagging, fat volume, and facial bone structure. At Carin Clinic, we avoid assembly-line treatments. Instead, we meticulously analyze each patient's unique skin condition to establish the optimal, customized synergy plan.
If looking in the mirror has become a source of stress due to skin aging, please feel free to visit us anytime. I will do my absolute best to help you rediscover your most beautiful years.
This has been Dr. Seojin Jae, Chief Dermatologist at Karin Clinic.
Thank you.
Hello, I am Dr. Seojin Jae, Chief Dermatologist at Karin Clinic.
When meeting patients in my clinic, I very frequently hear the same concern: "Doctor, I feel like my facial contour is collapsing, and at the same time, my skin feels dull and dry. What should I do?" This happens because aging never shows up in just one form. The sagging of skin caused by gravity and the thinning of skin accompanied by fine lines due to the loss of moisture and collagen usually progress simultaneously.
In these cases, the combination I recommend most confidently and frequently is the synergistic pairing of 'Ultherapy' and 'Rejuran.' Today, I will explain in detail why the effects are maximized when these two titans of anti-aging treatments come together.
1. Ultherapy: Lifting That Rebuilds the Pillars Deep Within the Skin
Ultherapy is a lifting device that utilizes High-Intensity Focused Ultrasound (HIFU) energy. Much like focusing sunlight through a magnifying glass to burn a spot on a piece of paper, it concentrates ultrasound energy onto deep target layers within the skin to create thermal coagulation points. The greatest feature of Ultherapy is that it delivers energy all the way down to the SMAS (Superficial Muscular Aponeurotic System) layerโthe exact deep layer pulled during a surgical faceliftโwithout causing any damage to the skin surface.
As the heated tissue contracts, it creates an immediate tightening effect. Over the following months, as new collagen and elastin regenerate, sagging eyes, eyelids, cheeks, double chins, and jawlines become smoothly lifted.
Simply put, Ultherapy plays the role of firmly rebuilding the collapsed "pillars" and structural framework inside skin that has succumbed to aging.
2. Rejuran: A Skin Booster That Fundamentally Improves the Dermal Environment
Rejuran is a treatment that directly injects PN (Polynucleotide), a biocompatible substance extracted from salmon DNA, into the dermal layer. While Ultherapy targets the deep muscular framework, Rejuran directly targets the dermisโthe layer we commonly refer to as the actual "skin texture."
By inducing regeneration in a damaged and thinned dermal layer, it increases skin thickness, balances oil and moisture levels, and strengthens the skin barrier. It restores the overall skin "texture" and "glow" by improving fine lines, minimizing pores, and clarifying the complexion.
Rejuran plays the role of adding premium fertilizer to a dry, barren "soil," transforming it into healthy, deeply hydrated skin.
3. Rebuilding the Framework and Completing the Interior: The Ultherapy + Rejuran Synergy
So, why is it so beneficial to receive these two treatments together? To jump straight to the conclusion: it is because they target completely different skin layers and their complementary roles match perfectly. I often compare this combination to "remodeling a house."
๐ Synergy Point 1: Three-Dimensional (3D) Anti-Aging (The Difference in Depth)
When a house is old and deteriorating, simply replacing the wallpaper (the surface) won't make the structure sturdy, and rebuilding just the pillars (the framework) won't make the interior beautiful. While Ultherapy pulls up sagging tissue from the deepest layer (SMAS) to define the facial "contour," Rejuran densely fills the middle layer (dermis) to smooth out the skin's "texture." By tackling both the deep and shallow layers at once, a flawless anti-aging transformation is achieved.
๐ Synergy Point 2: Maximizing Collagen Production
Ultherapy triggers natural collagen production through thermal stimulation. For skin cells to actively produce collagen during this process, premium "materials" and a healthy "environment" are absolutely essential. Rejuran (the PN component) provides precisely those excellent raw materials and the ideal regenerative environment. If Ultherapy flips the switch to start up the factory, Rejuran pours in the high-grade raw materials. Consequently, you can expect a much faster and more powerful skin regeneration and elasticity boost compared to receiving either treatment alone.
๐ Synergy Point 3: Compensating for Post-Treatment Dryness
After receiving energy-based laser or ultrasound treatments like Ultherapy, some patients temporarily experience dryness because the moisture inside the skin evaporates. Combining this with Rejuranโwhich possesses outstanding moisture-retention and regenerative capabilitiesโperfectly guards against post-laser dryness, while accelerating skin soothing and recovery.
4. Ideal Candidates for the Ultherapy + Rejuran Combination
This perfect synergistic combination is highly recommended for those who:
Are concerned about a collapsing facial line and a dulled, sagging jawline.
Have thin, dry skin that feels like it is losing its elasticity and sagging helplessly.
Notice a prominent increase in shallow fine lines all over the face, especially around the eyes and mouth.
Want their peak skin condition and crisp facial contours ahead of a wedding or a major event.
Lack the time to undergo multiple separate treatments and want definitive, comprehensive results all at once.
When it comes to anti-aging, a simple, one-dimensional approachโlike erasing a single wrinkle or just pulling the skin tightโcannot bring out natural beauty. You must simultaneously improve the structural issues deep within the skin along with the visible quality of the skin surface to truly restore your natural, youthful, and effortless beauty.
Of course, no matter how excellent a treatment combination is, the procedure design, energy distribution, and injection volume must be delicately tailored to each individual's skin thickness, degree of sagging, fat volume, and facial bone structure. At Carin Clinic, we avoid assembly-line treatments. Instead, we meticulously analyze each patient's unique skin condition to establish the optimal, customized synergy plan.
If looking in the mirror has become a source of stress due to skin aging, please feel free to visit us anytime. I will do my absolute best to help you rediscover your most beautiful years.
This has been Dr. Seojin Jae, Chief Dermatologist at Karin Clinic.
Thank you.