DOCTOR'S COLUMN

Rejuran Healer vs. Rejuran HB Plus: The Ultimate Guide to Pain and Efficacy

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Hello, I am Seojin Jae, the Chief Dermatologist at Myeongdong Karin Clinic, where we dedicate our expertise to the fundamental health of your skin.


When conducting anti-aging consultations in my clinic, one of the most frequently requested skin booster treatments is "Rejuran." However, despite its outstanding efficacy and stellar reputation, there is a significant barrier that makes many patients hesitant: the pain.


"I heard Rejuran hurts enough to make you cry. Will I be able to handle it?"


Whenever I see patients worrying about this, I feel deeply sympathetic as a doctor. Therefore, to help you overcome your fear of pain and make an informed, smart choice tailored to your skin condition, I would like to clearly break down the differences between the original Rejuran Healer and Rejuran HB Plus, which is highly popular for its reduced pain and enhanced patient satisfaction.


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1. Rejuran Healer: The Standard of Anti-Aging and Skin Regeneration

Rejuran Healer is the original skin booster, consisting of 100% PN (Polynucleotide)—a biocompatible substance extracted from salmon DNA.


Doctor’s Note: "By directly supplying nutrients to the thinned dermal layer, it firmly rebuilds a collapsed skin barrier. It is literally the most excellent treatment for the 'foundational groundwork' of your skin."


Key Benefits: Fundamental improvement of fine lines and elasticity, pore reduction, and normalization of the oil-water balance.


The Downside: Because it is a highly concentrated skin regeneration substance, the particle size is large and the viscosity is high. As this substance is injected into the dermal layer, it creates pressure that causes a fairly intense, stiff, and stinging pain.


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2. Rejuran HB Plus (Hydro Booster): Half the Pain, Double the Hydration

Rejuran HB Plus was created specifically for those who want the powerful regenerative effects of Rejuran Healer but have been putting off the treatment due to the pain. It combines the original PN component with Hyaluronic Acid (HA)—which intensely attracts moisture—and Lidocaine (a local anesthetic) in an optimal ratio.


Doctor’s Note: "Because it contains its own numbing component, patients report that the actual pain they feel during the procedure drops to less than half compared to the original Rejuran Healer. It can be received comfortably with just topical numbing cream."


Key Benefits: Maintains the regenerative effects of Polynucleotide while instantly resolving deep skin dryness and providing a radiant, "glass skin" (moisture-glow) effect.


Strengths: Since the burden of pain is minimal, it is highly suitable for receiving consistent, periodic anti-aging maintenance.


3. Which Rejuran is Right for Me?

When comparing Rejuran Healer and Rejuran HB Plus in the clinic, I never say, "One is unconditionally better than the other." This is because the ideal prescription varies depending on the patient's current skin condition and priorities. While Rejuran Healer has the disadvantage of greater pain, its single PN component offers a more powerful skin regeneration (restoration) effect.


Treatment
Recommended For
Rejuran Healer

Those who want the most powerful skin regeneration and fundamental anti-aging improvement, even if it means enduring the pain, Those with thin, highly damaged skin.

Rejuran HB Plus

Those who are highly sensitive to pain, Those who want fine line improvement along with instant deep hydration to treat severe inner dryness.


In the end, the most important step is a thorough consultation with a medical professional who can accurately diagnose your skin condition. Rather than blindly following a treatment just because others say it is good, I recommend choosing the most effective skin booster by comprehensively assessing your current skin thickness, degree of elasticity loss, and dryness.


If you are still hesitating to try Rejuran due to a fear of pain, please do not hesitate to visit us for a consultation. Avoiding any overtreatment, I will guide you toward comfortable anti-aging care through honest procedures tailored strictly to your needs, backed by our expertise in minimizing pain.


This has been Seojin Jae, Chief Dermatologist at Myeongdong Karin Clinic.

Thank you.

Location

Address:

4F, Serim Building, 18 Myeongdong 10-gil, Seoul

Transportation:

Myeongdong Station (Line 4) Exit 8

Euljiro 1(il)-ga Station (Line 2) Exit 6


Clinic Hours

Weekdays: 10:00 AM - 8:00 PM

Weekends: 10:00 AM - 4:00 PM

※ Closed every Wednesday and Sunday.